SZL P1-41

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Selleck Chemicals

SKU:S9724-5MG

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SZL P1-41 is an inhibitor of E3 Ligase used in studies of Apoptosis and Protein Degradation / Proteasome. It is especially relevant in apoptosis, cancer, and protein homeostasis models, where defined compound exposure can be linked to caspase-associated cell-death signaling and survival decisions and ubiquitin-dependent turnover, proteostasis, and targeted protein degradation.

By inhibiting E3 Ligase, SZL P1-41 can be used to examine caspase-associated cell-death signaling and survival decisions and ubiquitin-dependent turnover, proteostasis, and targeted protein degradation. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and protein homeostasis models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving E3 Ligase
  • Pathway perturbation studies connected to Apoptosis and Protein Degradation / Proteasome
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, SZL P1-41 is appropriate when a defined chemical perturbant is needed to connect E3 Ligase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and protein homeostasis models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
E3 Ligase
Target Class:
Enzyme
Pathways:
Apoptosis • Protein Degradation / Proteasome
Research Area:
Apoptosis • Cancer • Protein Homeostasis • Stem Cell Biology
CAS No.:
222716-34-9
Molecular Weight:
420.52
Formula:
C₂₄H₂₄N₂O₃S
SMILES:
CCC1=C(O)C(=C2OC=C(C(=O)C2=C1)C3=NC4=C(S3)C=CC=C4)CN5CCCCC5
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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