TAK-901

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Selleck Chemicals

S2718-5MG

€167,00 EUR
€167,00 EUR
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TAK-901 is an inhibitor of Aurora Kinases and JAK2 and related targets used in studies of MAPK / ERK Signaling and JAK-STAT Signaling and related signaling programs. It is especially relevant in cancer, cell cycle, and cell signaling models, where defined compound exposure can be linked to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and cytokine-responsive transcriptional signaling and immune regulation.

By inhibiting Aurora Kinases and JAK2 and related targets, TAK-901 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and cytokine-responsive transcriptional signaling and immune regulation. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell cycle, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Aurora Kinases and JAK2 and related targets
  • Pathway perturbation studies connected to MAPK / ERK Signaling and JAK-STAT Signaling and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, TAK-901 is appropriate when a defined chemical perturbant is needed to connect Aurora Kinases and JAK2 and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Aurora Kinases • JAK2 • AURKA
Target Class:
Kinase
Pathways:
MAPK / ERK Signaling • JAK-STAT Signaling • Cell Cycle Regulation
Research Area:
Cancer • Cell Cycle • Cell Signaling • Immunology
CAS No.:
934541-31-8
Molecular Weight:
504.64
Formula:
C₂₈H₃₂N₄O₃S
SMILES:
CCS(=O)(=O)C1=CC=CC(=C1)C2=CC(=C(C3=C2C4=C(N3)N=CC(=C4)C)C)C(=O)NC5CCN(CC5)C
InChIKey:
WKDACQVEJIVHMZ-UHFFFAOYSA-N
PubChem:
16124208
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.