Tamoxifen

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Selleck Chemicals

S1238-500MG

€144,00 EUR
€144,00 EUR
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Tamoxifen is a modulator of Estrogen Receptor used in studies of Hormone Signaling. It is especially relevant in angiogenesis, cancer, and endocrinology models, where defined compound exposure can be linked to ligand-dependent transcriptional programs and endocrine regulation.

By modulating Estrogen Receptor, Tamoxifen can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In angiogenesis, cancer, and endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Estrogen Receptor
  • Pathway perturbation studies connected to Hormone Signaling
  • Context-dependent response profiling and mechanism comparison
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, Tamoxifen is appropriate when a defined chemical perturbant is needed to connect Estrogen Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis, cancer, and endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Estrogen Receptor
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling
Research Area:
Angiogenesis • Cancer • Endocrinology • Infectious Disease
CAS No.:
10540-29-1
Molecular Weight:
371.51
Formula:
C₂₆H₂₉NO
SMILES:
CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3
InChIKey:
NKANXQFJJICGDU-QPLCGJKRSA-N
PubChem:
2733526
Storage Temperature:
4°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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