Tegatrabetan (BC-2059)

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Selleck Chemicals

S0733-5MG

€363,00 EUR
€363,00 EUR
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Tegatrabetan (BC-2059) is an antagonist of Wnt / beta-catenin used in studies of Wnt Signaling. It is especially relevant in cancer, cell signaling, and developmental biology models, where defined compound exposure can be linked to beta-catenin-dependent transcription and developmental signaling.

By blocking Wnt / beta-catenin, Tegatrabetan (BC-2059) can be used to examine beta-catenin-dependent transcription and developmental signaling. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and developmental biology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Wnt / beta-catenin
  • Pathway perturbation studies connected to Wnt Signaling
  • Receptor-blockade and ligand-competition studies
  • Pathway-reporter and mechanistic-phenotyping studies

Overall, Tegatrabetan (BC-2059) is appropriate when a defined chemical perturbant is needed to connect Wnt / beta-catenin with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and developmental biology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Wnt / beta-catenin
Target Class:
Signaling Pathway Modulator
Pathways:
Wnt Signaling
Research Area:
Cancer • Cell Signaling • Developmental Biology • Stem Cell Biology
CAS No.:
1227637-23-1
Molecular Weight:
588.74
Formula:
C₂₈H₃₆N₄O₆S₂
SMILES:
CC1CC(CN(C1)S(=O)(=O)C2=CC3=C(C=C2)C(=C4C=CC(=CC4=C3N=O)S(=O)(=O)N5CC(CC(C5)C)C)NO)C
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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