Telaglenastat (CB-839)

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Selleck Chemicals

SKU:S7655-5MG

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Telaglenastat (CB-839) is an inhibitor linked to Autophagy and related pathway-oriented research. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to autophagic flux, lysosomal turnover, and stress adaptation in autophagy models.

The pathway annotation connects Telaglenastat (CB-839) to Autophagy, supporting experiments that monitor autophagic flux, lysosomal turnover, and stress adaptation across biochemical, cellular, or phenotypic assay formats. This context is compatible with autophagy-flux, lysosome, and cargo-clearance assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In autophagy models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Pathway perturbation studies connected to Autophagy
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in autophagy models
  • Combination studies with orthogonal perturbagens

Overall, Telaglenastat (CB-839) is well suited to pathway-oriented studies that need a defined compound input for Autophagy readouts in autophagy models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Pathways:
Autophagy
Research Area:
Autophagy
CAS No.:
1439399-58-2
Molecular Weight:
571.57
Formula:
C₂₆H₂₄F₃N₇O₃S
SMILES:
C1=CC=NC(=C1)CC(=O)NC2=NN=C(S2)CCCCC3=NN=C(C=C3)NC(=O)CC4=CC(=CC=C4)OC(F)(F)F
InChIKey:
PRAAPINBUWJLGA-UHFFFAOYSA-N
PubChem:
15232
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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