Tetraspanin-24 (TSPAN24 or CD151) Antibody - FFPE Validated

Biological Background

This antibody is suited for researchers who want to evaluate Tetraspanin-24 (CD151) and relate it to cell-state biology. Tetraspanin-24 is a cell-surface or matrix-associated protein that mediates adhesion and outside-in signaling. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.

In some datasets and protocols, it is referenced by the gene symbol CD151.

Use in the Laboratory

Because adhesion complexes are dynamic, timing and confluence can strongly influence measured signal. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.

Many targets show context-dependent localization, so comparisons across matched conditions can reveal meaningful patterns.

To keep datasets interpretable, labs often document:

• effects of adhesion inhibitors or matrix composition
• focal adhesion versus diffuse membrane distribution
• remodeling after changes in substrate or mechanical stress

Version Notes

Because fixation can mask epitopes, fixed-section oriented formats aim to maintain recognition after standard deparaffinization and retrieval steps. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding. Small differences in preparation can reshape apparent localization, so interpret results in context.

If your study spans multiple model systems, it can help to define a shared reference condition for Tetraspanin-24 so cross-sample contrasts stay meaningful.

As you refine hypotheses around Tetraspanin-24 (CD151), the fixed-section format helps keep conclusions tied to preparation context.