Tetraspanin-26 (TSPAN26 or CD37) Antibody

Biological Background

Designed to help you explore Tetraspanin-26, this antibody supports studies where protein context matters. Tetraspanin-26 is a cell-surface or matrix-associated protein that mediates adhesion and outside-in signaling. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.

In some datasets and protocols, it is referenced by the gene symbol CD37.

Use in the Laboratory

Perturbations that disrupt integrin engagement or actomyosin tension can reshape localization and complex assembly. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.

Many targets show context-dependent localization, so comparisons across matched conditions can reveal meaningful patterns.

To keep datasets interpretable, labs often document:

• co-variation with cytoskeletal and scaffold partners
• effects of adhesion inhibitors or matrix composition
• focal adhesion versus diffuse membrane distribution

Version Notes

When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding. Small differences in preparation can reshape apparent localization, so interpret results in context.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Tetraspanin-26 patterns can be compared across experiments without guesswork.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Tetraspanin-26 patterns can be compared across experiments without guesswork.

The regular format version supports deeper biological narratives around Tetraspanin-26 without overcomplicating setup.