Tetraspanin-29 (TSPAN29 or CD9) Antibody - FFPE Validated
BiCell Scientific
SKU:10229-FFPE-50UL
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Scientific Overview
Designed to help you assess Tetraspanin-29, this antibody supports studies where protein context matters. Tetraspanin-29 is a matrix-interaction protein often examined in migration and morphogenesis models. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol CD9.
Research Relevance
Perturbations that disrupt integrin engagement or actomyosin tension can reshape localization and complex assembly. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling. In oncology research models, expression shifts can accompany changes in adhesion, signaling, or differentiation state.
When building a narrative around the target, it helps to track:
- co-variation with cytoskeletal and scaffold partners
- focal adhesion versus diffuse membrane distribution
- effects of adhesion inhibitors or matrix composition
Application-Specific Context
In sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
When interpreting Tetraspanin-29, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
The fixed-section version supports deeper biological narratives around Tetraspanin-29 without overcomplicating setup.
- Targets:
- CD9
- Research Area:
- Cancer • Developmental Biology • Immunology
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (12-aa) derived from the N-terminal cytoplasmic region of mouse CD9 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P21926
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 91.7% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C