Tetraspanin-30 (TSPAN30 or CD63) Antibody - FFPE Validated
BiCell Scientific
SKU:10230-FFPE-50UL
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About the Target
This antibody helps you explore Tetraspanin-30 (CD63) while keeping condition-to-condition contrasts straightforward. Tetraspanin-30 is an extracellular or receptor-linked component that coordinates matrix engagement with cytoskeletal remodeling. Use matched handling so differences reflect biology rather than processing.
In some datasets and protocols, it is referenced by the gene symbol CD63.
Research Context
Perturbations that disrupt integrin engagement or actomyosin tension can reshape localization and complex assembly. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows. In oncology research models, expression shifts can accompany changes in adhesion, signaling, or differentiation state.
Consider these angles when interpreting target-level changes:
- remodeling after changes in substrate or mechanical stress
- effects of adhesion inhibitors or matrix composition
- co-variation with cytoskeletal and scaffold partners
- focal adhesion versus diffuse membrane distribution
Variant Considerations
For paraffin-embedded samples, fixation history and retrieval strategy matter; this option is aligned to those constraints. This matters because epitope exposure and background can vary with preparation and extraction steps. Standardize key parameters so differences reflect biology rather than handling.
When interpreting Tetraspanin-30, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
When interpreting Tetraspanin-30, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
With consistent handling, the fixed-section format can make Tetraspanin-30 (CD63) comparisons easier to reproduce across runs.
- Targets:
- CD63
- Research Area:
- Cancer • Developmental Biology • Immunology
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the C-terminal cytoplasmic region of human Tetraspanin-30 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P08962
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C