Tetraspanin-7 (TSPAN7) Antibody - FFPE Validated
BiCell Scientific
SKU:10207-FFPE-50UL
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About the Target
Use this antibody to examine Tetraspanin-7 in your model system. Tetraspanin-7 is a cell-surface or matrix-associated protein that mediates adhesion and outside-in signaling. Look for shifts in distribution that track with phenotype changes.
In some datasets and protocols, it is referenced by the gene symbol TSPAN7.
Research Context
Perturbations that disrupt integrin engagement or actomyosin tension can reshape localization and complex assembly. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Consider these angles when interpreting target-level changes:
- focal adhesion versus diffuse membrane distribution
- co-variation with cytoskeletal and scaffold partners
- remodeling after changes in substrate or mechanical stress
- effects of adhesion inhibitors or matrix composition
Variant Considerations
In sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
When interpreting Tetraspanin-7, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Tetraspanin-7 patterns can be compared across experiments without guesswork.
With a clear focus on Tetraspanin-7, this fixed-section option fits streamlined studies and fast iteration.
- Targets:
- TSPAN7
- Research Area:
- Developmental Biology
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the C-terminal cytoplasmic region of human Tetraspanin-7 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P41732
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C