TH287

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Selleck Chemicals

S7631-10MG

€144,00 EUR
€144,00 EUR
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TH287 is an inhibitor linked to DNA Damage Response and related pathway-oriented research. In practice, this places the compound in experiments that measure checkpoint activation, DNA repair, and genome-stability control in cancer and dna damage / repair models.

The pathway annotation connects TH287 to DNA Damage Response, supporting experiments that monitor checkpoint activation, DNA repair, and genome-stability control across biochemical, cellular, or phenotypic assay formats. This context is compatible with DNA-repair, checkpoint, and genotoxic-stress assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In cancer and dna damage / repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Pathway perturbation studies connected to DNA Damage Response
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in cancer and dna damage / repair models
  • Combination studies with orthogonal perturbagens

Overall, TH287 is well suited to pathway-oriented studies that need a defined compound input for DNA Damage Response readouts in cancer and dna damage / repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Pathways:
DNA Damage Response
Research Area:
Cancer • DNA Damage / Repair
CAS No.:
1609960-30-6
Molecular Weight:
269.13
Formula:
C₁₁H₁₀Cl₂N₄
SMILES:
CNC1=NC(=NC(=C1)C2=C(C(=CC=C2)Cl)Cl)N
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.