tirabrutinib (ONO-4059)hydrochloride

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Selleck Chemicals

S8166-5MG

€144,00 EUR
€144,00 EUR
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tirabrutinib (ONO-4059)hydrochloride is an inhibitor of BTK used in studies of Immune Signaling. In practice, this places the compound in experiments that measure cytokine-mediated signaling and inflammatory effector responses in angiogenesis, cancer, and cell signaling models.

By inhibiting BTK, tirabrutinib (ONO-4059)hydrochloride can be used to examine cytokine-mediated signaling and inflammatory effector responses. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In angiogenesis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving BTK
  • Pathway perturbation studies connected to Immune Signaling
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, tirabrutinib (ONO-4059)hydrochloride is appropriate when a defined chemical perturbant is needed to connect BTK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
BTK
Target Class:
Kinase
Pathways:
Immune Signaling
Research Area:
Angiogenesis • Cancer • Cell Signaling • Immunology
CAS No.:
1439901-97-9
Molecular Weight:
490.94
Formula:
C₂₅H₂₂N₆O₃·HCl
SMILES:
CC#CC(=O)N1CCC(C1)N2C3=NC=NC(=C3N(C2=O)C4=CC=C(C=C4)OC5=CC=CC=C5)N.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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