Tisotumab Vedotin
Selleck Chemicals
SKU:D4051-1MG
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Tisotumab Vedotin is an antibody-drug conjugate (ADC) composed of a fully human monoclonal antibody to tissue factor III (thromboplastin) also known as CD142, conjugated to monomethyl auristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinylp-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker.
Product overview
Tisotumab vedotin is relevant to research on solid tumors mainly in cervical cancer. The product background identifies the antibody component, target antigen and payload or linker architecture where these details are supplied. This ADC context supports comparison of antigen recognition, payload conjugation and cellular uptake behavior in controlled assay systems, especially when researchers need to distinguish conjugated biologics from unconjugated antibodies or standalone small molecules.
Laboratory context
The listed workflow context supports binding and uptake-oriented laboratory studies where a defined antibody component, cellular target and conjugated payload are relevant to assay planning, including cell-surface binding, cell-uptake and protein-binding experiments, within oncology research.
- Research Area:
- Oncology
- Application:
- Cell Surface Binding • Cell Uptake Studies • Protein Binding
- Formulation:
- 1xPBS
- CAS No.:
- 1418731-10-8
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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