Toll-like receptor 2 (TLR2 or CD282) Antibody - Western Blot Validated
BiCell Scientific
SKU:64102-WB-50UL
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Scientific Overview
This antibody supports efforts to explore Toll-like receptor 2 (TLR2) and interpret it within interaction networks. Toll-like receptor 2 is an immune-related target that can reflect differentiation, activation, or trafficking behavior. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
In some datasets and protocols, it is referenced by the gene symbol TLR2.
Research Relevance
Immune markers are often interpreted alongside a panel of complementary targets to improve population resolution. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
When cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood.
When building a narrative around the target, it helps to track:
- activation-dependent changes across stimulation conditions
- assessment of surface versus internalized pools
- panel-based interpretation with additional lineage markers
Application-Specific Context
When samples are prepared in reducing conditions, some epitopes become more accessible; this version is designed with that context in mind. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. If signaling is transient, sampling time can be as important as condition.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Toll-like receptor 2 patterns can be compared across experiments without guesswork.
Use the denaturing-format version to relate Toll-like receptor 2 (TLR2) behavior to upstream cues and downstream consequences.
- Targets:
- TLR2
- Research Area:
- Cell Signaling • Developmental Biology • Immunology • Inflammation
- Application:
- WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the C-terminal cytoplasmic region of human TLR2 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- O60603
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C