Toll-like receptor 3 (TLR3 or CD283) Antibody - FFPE Validated
BiCell Scientific
SKU:64103-FFPE-50UL
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Protein Function
Bring Toll-like receptor 3 into view to explore changes across conditions. Toll-like receptor 3 is an immune-related target that can reflect differentiation, activation, or trafficking behavior. Look for shifts in distribution that track with phenotype changes.
In some datasets and protocols, it is referenced by the gene symbol TLR3.
Experimental Applications
Immune markers are often interpreted alongside a panel of complementary targets to improve population resolution. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
In practice, target tracking can support localization mapping, relative quantification, and interaction-focused experiments without locking you into a single readout strategy.
Common experimental questions that benefit from target tracking include:
- activation-dependent changes across stimulation conditions
- panel-based interpretation with additional lineage markers
- comparisons across differentiation or polarization states
- assessment of surface versus internalized pools
Workflow Perspective
Because fixation can mask epitopes, fixed-section oriented formats aim to maintain recognition after standard deparaffinization and retrieval steps. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.
If your study spans multiple model systems, it can help to define a shared reference condition for Toll-like receptor 3 so cross-sample contrasts stay meaningful.
For challenging targets, pairing Toll-like receptor 3 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
With a clear focus on Toll-like receptor 3, this fixed-section option fits streamlined studies and fast iteration.
- Targets:
- TLR3
- Research Area:
- Cell Signaling • Developmental Biology • Immunology • Inflammation
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (18-aa) derived from the C-terminal cytoplasmic region of human TLR3 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- O15455
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C