Toll-like receptor 6 (TLR6 or CD286) Antibody
BiCell Scientific
SKU:64106-50UL
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Biological Background
This antibody is suited for researchers who want to evaluate Toll-like receptor 6 (TLR6) and relate it to cell-state biology. Toll-like receptor 6 is a surface or signaling marker used to characterize immune cell subsets and activation states. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol TLR6.
Use in the Laboratory
Comparisons across tissues or culture conditions can highlight activation-dependent shifts in expression. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Interpreting changes can benefit from separating expression differences from redistribution, particularly when the target cycles between compartments.
To keep datasets interpretable, labs often document:
- assessment of surface versus internalized pools
- panel-based interpretation with additional lineage markers
- comparisons across differentiation or polarization states
Version Notes
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding. Small differences in preparation can reshape apparent localization, so interpret results in context.
If your study spans multiple model systems, it can help to define a shared reference condition for Toll-like receptor 6 so cross-sample contrasts stay meaningful.
As you refine hypotheses around Toll-like receptor 6 (TLR6), the regular format format helps keep conclusions tied to preparation context.
- Targets:
- TLR6
- Research Area:
- Cell Signaling • Developmental Biology • Immunology • Inflammation
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the C-terminal cytoplasmic region of human TLR6 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9Y2C9
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C