Toll-like receptor 6 (TLR6 or CD286) Antibody - Western Blot Validated
BiCell Scientific
SKU:64106-WB-50UL
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Scientific Overview
For consistent comparison across experiments, use this antibody to examine Toll-like receptor 6 (TLR6) with a repeatable workflow. Toll-like receptor 6 is an immune-related target that can reflect differentiation, activation, or trafficking behavior. For comparison-heavy studies, consistent sample handling and normalization help reduce run-to-run drift.
In some datasets and protocols, it is referenced by the gene symbol TLR6.
Research Relevance
Immune markers are often interpreted alongside a panel of complementary targets to improve population resolution. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling.
When building a narrative around the target, it helps to track:
- assessment of surface versus internalized pools
- activation-dependent changes across stimulation conditions
- comparisons across differentiation or polarization states
- panel-based interpretation with additional lineage markers
Application-Specific Context
This denaturing-format version is geared toward targets presented after reduction and denaturation, where epitope exposure can shift from native conformations. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. A short pilot series can help set exposure ranges and reduce reruns.
For challenging targets, pairing Toll-like receptor 6 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
For multi-run studies, the denaturing-format option helps keep Toll-like receptor 6 (TLR6) trends comparable from experiment to experiment.
- Targets:
- TLR6
- Research Area:
- Cell Signaling • Developmental Biology • Immunology • Inflammation
- Application:
- WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the C-terminal cytoplasmic region of human TLR6 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9Y2C9
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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