Toll-like receptor 7 (TLR7 or CD287) Antibody
BiCell Scientific
SKU:64107-50UL
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Scientific Overview
Build reproducible readouts by using this antibody to investigate Toll-like receptor 7 (TLR7) across matched sample sets. Toll-like receptor 7 is a lineage-associated marker that supports stratification of immune populations in model systems. Use matched handling so differences reflect biology rather than processing.
In some datasets and protocols, it is referenced by the gene symbol TLR7.
Research Relevance
Comparisons across tissues or culture conditions can highlight activation-dependent shifts in expression. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling.
When building a narrative around the target, it helps to track:
- activation-dependent changes across stimulation conditions
- assessment of surface versus internalized pools
- comparisons across differentiation or polarization states
- panel-based interpretation with additional lineage markers
Application-Specific Context
For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. A short pilot series can help set exposure ranges and reduce reruns.
For challenging targets, pairing Toll-like receptor 7 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
With consistent handling, the regular format format can make Toll-like receptor 7 (TLR7) comparisons easier to reproduce across runs.
- Targets:
- TLR7
- Research Area:
- Cell Signaling • Developmental Biology • Immunology • Inflammation
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the C-terminal cytoplasmic region of mouse TLR7 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9NYK1
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 93.3% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C