Toll-like receptor 8 (TLR8 or CD288) Antibody
BiCell Scientific
SKU:64108-50UL
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About the Target
To connect mechanism with measurement, this antibody lets you examine Toll-like receptor 8 in pathway-driven studies. Toll-like receptor 8 is a surface or signaling marker used to characterize immune cell subsets and activation states. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
In some datasets and protocols, it is referenced by the gene symbol TLR8.
Research Context
Comparisons across tissues or culture conditions can highlight activation-dependent shifts in expression. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Consider these angles when interpreting target-level changes:
- assessment of surface versus internalized pools
- comparisons across differentiation or polarization states
- panel-based interpretation with additional lineage markers
Variant Considerations
For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
For challenging targets, pairing Toll-like receptor 8 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
For challenging targets, pairing Toll-like receptor 8 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Use the regular format version to relate Toll-like receptor 8 behavior to upstream cues and downstream consequences.
- Targets:
- TLR8
- Research Area:
- Cell Signaling • Developmental Biology • Immunology • Inflammation
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (17-aa) derived from the C-terminal cytoplasmic region of human TLR8 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9NR97
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C