Torkinib (PP242)

1 1

Selleck Chemicals

S2218-5MG

€144,00 EUR
€144,00 EUR
Sale Sold out
Taxes included. Shipping calculated at checkout.
Size
View full details

Torkinib (PP242) is an inhibitor of MTOR used in studies of PI3K-Akt-mTOR Signaling and Apoptosis and related signaling programs. It is especially relevant in apoptosis, autophagy, and cancer models, where defined compound exposure can be linked to growth-factor signaling, survival control, and nutrient-sensing outputs and caspase-associated cell-death signaling and survival decisions.

By inhibiting MTOR, Torkinib (PP242) can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and caspase-associated cell-death signaling and survival decisions. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, autophagy, and cancer models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving MTOR
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and Apoptosis and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Torkinib (PP242) is appropriate when a defined chemical perturbant is needed to connect MTOR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, autophagy, and cancer models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
MTOR
Target Class:
Kinase
Pathways:
PI3K-Akt-mTOR Signaling • Apoptosis • Autophagy
Research Area:
Apoptosis • Autophagy • Cancer • Cell Signaling
CAS No.:
1092351-67-1
Molecular Weight:
308.34
Formula:
C₁₆H₁₆N₆O
SMILES:
CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC4=C(N3)C=CC(=C4)O)N
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.