TPCA-1

1 1

Selleck Chemicals

S2824-10MG

€167,00 EUR
€167,00 EUR
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TPCA-1 is an inhibitor of IKK and NF-kB and related targets used in studies of JAK-STAT Signaling and NF-kB Signaling and related signaling programs. It is especially relevant in apoptosis, cancer, and cell signaling models, where defined compound exposure can be linked to cytokine-responsive transcriptional signaling and immune regulation and inflammatory transcriptional control and stress-responsive survival signaling.

By inhibiting IKK and NF-kB and related targets, TPCA-1 can be used to examine cytokine-responsive transcriptional signaling and immune regulation and inflammatory transcriptional control and stress-responsive survival signaling. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving IKK and NF-kB and related targets
  • Pathway perturbation studies connected to JAK-STAT Signaling and NF-kB Signaling and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Pathway-reporter and mechanistic-phenotyping studies

Overall, TPCA-1 is appropriate when a defined chemical perturbant is needed to connect IKK and NF-kB and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
IKK • NF-kB • STAT
Target Class:
Signaling Pathway Modulator
Pathways:
JAK-STAT Signaling • NF-kB Signaling • Immune Signaling
Research Area:
Apoptosis • Cancer • Cell Signaling • Immunology
CAS No.:
507475-17-4
Molecular Weight:
279.29
Formula:
C₁₂H₁₀FN₃O₂S
SMILES:
C1=CC(=CC=C1C2=CC(=C(S2)NC(=O)N)C(=O)N)F
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.