TPEN

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Selleck Chemicals

S6962-25MG

€144,00 EUR
€144,00 EUR
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TPEN is a modulator of NOS used in studies of DNA Damage Response and Apoptosis and related signaling programs. It is especially relevant in apoptosis, cancer, and cardiovascular models, where defined compound exposure can be linked to checkpoint activation, DNA repair, and genome-stability control and caspase-associated cell-death signaling and survival decisions.

By modulating NOS, TPEN can be used to examine checkpoint activation, DNA repair, and genome-stability control and caspase-associated cell-death signaling and survival decisions. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and cardiovascular models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving NOS
  • Pathway perturbation studies connected to DNA Damage Response and Apoptosis and related signaling programs
  • Context-dependent response profiling and mechanism comparison
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, TPEN is appropriate when a defined chemical perturbant is needed to connect NOS with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cardiovascular models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
NOS
Target Class:
Enzyme
Pathways:
DNA Damage Response • Apoptosis • Oxidative Stress Response
Research Area:
Apoptosis • Cancer • Cardiovascular • DNA Damage / Repair
CAS No.:
16858-02-9
Molecular Weight:
424.54
Formula:
C₂₆H₂₈N₆
SMILES:
C(CN(CC1=NC=CC=C1)CC2=NC=CC=C2)N(CC3=NC=CC=C3)CC4=NC=CC=C4
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.