Trifluoperazine 2HCl

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Selleck Chemicals

SKU:S3201-50MG

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Trifluoperazine 2HCl is an inhibitor of Dopamine Receptors used in studies of GPCR Signaling and Neurotransmission. In practice, this places the compound in experiments that measure receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability in neuroscience models.

By inhibiting Dopamine Receptors, Trifluoperazine 2HCl can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Dopamine Receptors
  • Pathway perturbation studies connected to GPCR Signaling and Neurotransmission
  • Concentration-response inhibition and target-dependence studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, Trifluoperazine 2HCl is appropriate when a defined chemical perturbant is needed to connect Dopamine Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Dopamine Receptors
Target Class:
GPCR
Pathways:
GPCR Signaling • Neurotransmission
Research Area:
Neuroscience
CAS No.:
440-17-5
Molecular Weight:
480.42
Formula:
C₂₁H₂₄F₃N₃S·2HCl
SMILES:
CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F.Cl.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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