Trk-B (NTRK2) (C-Terminus) (Cytoplasmic) Antibody - FFPE Validated
BiCell Scientific
SKU:06022-FFPE-50UL
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About the Target
This antibody helps you analyze Trk-B C-Terminus (NTRK2) while keeping condition-to-condition contrasts straightforward. Trk-B C-Terminus is a signaling component often monitored in models of neuronal differentiation and plasticity. Use matched handling so differences reflect biology rather than processing.
In some datasets and protocols, it is referenced by the gene symbol NTRK2.
Research Context
Because many neuronal proteins form complexes, interpreting signal changes can benefit from complementary controls and timing. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
Consider these angles when interpreting target-level changes:
- interaction tendencies with scaffold or receptor partners
- activity-linked changes in abundance or distribution
- regional localization along neurites and synaptic compartments
- comparison across differentiation time courses
Variant Considerations
This fixed-section oriented version is intended for paraffin-embedded tissue, where crosslinking and retrieval steps can shape epitope accessibility. This matters because epitope exposure and background can vary with preparation and extraction steps. Standardize key parameters so differences reflect biology rather than handling.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Trk-B C-Terminus patterns can be compared across experiments without guesswork.
With consistent handling, the fixed-section format can make Trk-B C-Terminus (NTRK2) comparisons easier to reproduce across runs.
- Targets:
- NTRK2
- Research Area:
- Cancer • Cell Signaling • Developmental Biology • Neuroscience
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the C-terminal cytoplasmic region of mouse Trk-B protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q16620
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 84.6% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C