Trk-B (NTRK2) (C-Terminus) (Cytoplasmic) Antibody - Western Blot Validated
BiCell Scientific
SKU:06022-WB-50UL
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Scientific Overview
This antibody is suited for researchers who want to assess Trk-B C-Terminus and relate it to cell-state biology. Trk-B C-Terminus is a receptor or synapse-associated protein that supports neuronal signaling and connectivity. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Tracking Trk-B C-Terminus can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Research Relevance
Because many neuronal proteins form complexes, interpreting signal changes can benefit from complementary controls and timing. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
When building a narrative around the target, it helps to track:
- activity-linked changes in abundance or distribution
- regional localization along neurites and synaptic compartments
- comparison across differentiation time courses
Application-Specific Context
For size-resolved readouts under denaturing conditions, this version helps you focus on expected band patterns and molecular weight regions. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
If your study spans multiple model systems, it can help to define a shared reference condition for Trk-B C-Terminus so cross-sample contrasts stay meaningful.
The denaturing-format version supports deeper biological narratives around Trk-B C-Terminus without overcomplicating setup.
- Targets:
- NTRK2
- Research Area:
- Cancer • Cell Signaling • Developmental Biology • Neuroscience
- Application:
- WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the C-terminal cytoplasmic region of mouse Trk-B protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q16620
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 84.6% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C