Trk-B (NTRK2) (N-Terminus) (Extracellular) Antibody
BiCell Scientific
SKU:06022N-50UL
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Scientific Overview
This antibody is suited for researchers who want to assess Trk-B N-Terminus and relate it to cell-state biology. Trk-B N-Terminus is a neuron-enriched target connected to synaptic organization and signaling dynamics. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Tracking Trk-B N-Terminus can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Research Relevance
Because many neuronal proteins form complexes, interpreting signal changes can benefit from complementary controls and timing. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
When building a narrative around the target, it helps to track:
- comparison across differentiation time courses
- regional localization along neurites and synaptic compartments
- activity-linked changes in abundance or distribution
Application-Specific Context
When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Trk-B N-Terminus patterns can be compared across experiments without guesswork.
The regular format version supports deeper biological narratives around Trk-B N-Terminus without overcomplicating setup.
- Targets:
- NTRK2
- Research Area:
- Cancer • Cell Signaling • Developmental Biology • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the N-terminal extracellular region of human Trk-B protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q16620
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C