Trpc5 (N-Terminus) Antibody - FFPE Validated
BiCell Scientific
SKU:11015N-FFPE-50UL
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Protein Function
For consistent comparison across experiments, use this antibody to investigate Trpc5 N-Terminus with a repeatable workflow. Trpc5 N-Terminus is a trafficking-sensitive transporter that can shift between intracellular pools and the plasma membrane. Use matched handling so differences reflect biology rather than processing.
Tracking Trpc5 N-Terminus can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Experimental Applications
Comparisons across tissues or engineered cell lines can help separate expression effects from localization effects. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.
Many workflows benefit from tracking both signal intensity and compartment distribution, especially when the target participates in multi-protein assemblies.
Common experimental questions that benefit from target tracking include:
- relative abundance across engineered constructs
- patterns consistent with apical or basolateral sorting
- surface versus intracellular pool distribution
- stimulus-dependent trafficking and turnover
Workflow Perspective
In sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. Document normalization choices so collaborators can reproduce the same interpretation.
For challenging targets, pairing Trpc5 N-Terminus measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
For multi-run studies, the fixed-section option helps keep Trpc5 N-Terminus trends comparable from experiment to experiment.
- Targets:
- TRPC5
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the N-terminal cytoplasmic region of human Trpc5 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9UL62
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C