Trpm2 Antibody - Western Blot Validated

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BiCell Scientific

SKU:11022-WB-50UL

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Size
Blocking Peptide
Quantity
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About the Target

Use this antibody to assess Trpm2 in your model system. Trpm2 is a membrane protein linked to solute movement and gradient maintenance. Focus on trends across conditions rather than single-point snapshots.

Following Trpm2 across perturbations can help separate expression effects from compartment shifts.

Research Context

Many transport proteins cycle through endosomal pathways, making localization a key readout alongside abundance. Pair measurements with orthogonal readouts when interpretation is sensitive to context.

Consider these angles when interpreting target-level changes:

  • surface versus intracellular pool distribution
  • patterns consistent with apical or basolateral sorting
  • relative abundance across engineered constructs
  • stimulus-dependent trafficking and turnover

Variant Considerations

If your primary readout depends on denatured protein presentation, this option can streamline comparison across lanes and conditions. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Trpm2 patterns can be compared across experiments without guesswork.

When interpreting Trpm2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Trpm2 patterns can be compared across experiments without guesswork.

Choose the denaturing-format option when you want Trpm2 results aligned to your sample format.

Targets:
TRPM2
Research Area:
Cell Signaling • Neuroscience
Application:
WB
Reactivity:
Human • Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (17-aa) derived from the C-terminal region of mouse Trpm2 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
O94759
Homology:
Synthetic peptide sequence is identical to rat sequence (shows 94.1% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C