Trpm6 Antibody
BiCell Scientific
SKU:11026-50UL
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Scientific Overview
This antibody supports efforts to assess Trpm6 and interpret it within interaction networks. Trpm6 is a trafficking-sensitive transporter that can shift between intracellular pools and the plasma membrane. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
Tracking Trpm6 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Research Relevance
Modulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
When cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood.
When building a narrative around the target, it helps to track:
- surface versus intracellular pool distribution
- relative abundance across engineered constructs
- stimulus-dependent trafficking and turnover
Application-Specific Context
When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. If signaling is transient, sampling time can be as important as condition.
For challenging targets, pairing Trpm6 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
The regular format option supports mechanistic reading of Trpm6 when interactions and context are the focus.
- Targets:
- TRPM6
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the C-terminal region of mouse Trpm6 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9BX84
- Homology:
- Synthetic peptide sequence is identical to rat sequence (shows 43.8% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C