Trpv2 Antibody
BiCell Scientific
SKU:11032-50UL
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Scientific Overview
This antibody helps you characterize Trpv2 while keeping condition-to-condition contrasts straightforward. Trpv2 is a membrane-embedded regulator of ionic or osmotic balance in cells. For comparison-heavy studies, consistent sample handling and normalization help reduce run-to-run drift.
Tracking Trpv2 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Research Relevance
Comparisons across tissues or engineered cell lines can help separate expression effects from localization effects. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling.
When building a narrative around the target, it helps to track:
- relative abundance across engineered constructs
- patterns consistent with apical or basolateral sorting
- surface versus intracellular pool distribution
- stimulus-dependent trafficking and turnover
Application-Specific Context
For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. A short pilot series can help set exposure ranges and reduce reruns.
When interpreting Trpv2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Pair this regular format format with stable controls to keep Trpv2 measurements coherent over time.
- Targets:
- TRPV2
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the C-terminal region of mouse Trpv2 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9Y5S1
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 60% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C