Trpv2 Antibody - FFPE Validated
BiCell Scientific
SKU:11032-FFPE-50UL
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Protein Function
When control selection matters, this antibody helps you examine Trpv2 in a structured study. Trpv2 is a membrane-embedded regulator of ionic or osmotic balance in cells. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.
Monitoring Trpv2 alongside context markers can improve interpretation when phenotypes are subtle.
Experimental Applications
Comparisons across tissues or engineered cell lines can help separate expression effects from localization effects. Time course design can be decisive when regulation is transient or compartment dependent.
In practice, target tracking can support localization mapping, relative quantification, and interaction-focused experiments without locking you into a single readout strategy.
Common experimental questions that benefit from target tracking include:
- stimulus-dependent trafficking and turnover
- surface versus intracellular pool distribution
- relative abundance across engineered constructs
Workflow Perspective
This fixed-section oriented version is intended for paraffin-embedded tissue, where crosslinking and retrieval steps can shape epitope accessibility. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. Predefine acceptance criteria for controls before collecting the full dataset.
If your study spans multiple model systems, it can help to define a shared reference condition for Trpv2 so cross-sample contrasts stay meaningful.
When interpreting Trpv2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Integrate the fixed-section version into your design so Trpv2 signals can be interpreted alongside matched controls.
- Targets:
- TRPV2
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the C-terminal region of mouse Trpv2 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9Y5S1
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 60% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C