Trpv5 Antibody
BiCell Scientific
SKU:11035-50UL
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Biological Background
Use this antibody to analyze Trpv5 in your model system. Trpv5 is a trafficking-sensitive transporter that can shift between intracellular pools and the plasma membrane. Focus on trends across conditions rather than single-point snapshots.
Monitoring Trpv5 alongside context markers can improve interpretation when phenotypes are subtle.
Use in the Laboratory
Modulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Many targets show context-dependent localization, so comparisons across matched conditions can reveal meaningful patterns.
To keep datasets interpretable, labs often document:
- surface versus intracellular pool distribution
- patterns consistent with apical or basolateral sorting
- relative abundance across engineered constructs
- stimulus-dependent trafficking and turnover
Version Notes
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Trpv5 patterns can be compared across experiments without guesswork.
If your study spans multiple model systems, it can help to define a shared reference condition for Trpv5 so cross-sample contrasts stay meaningful.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Trpv5 patterns can be compared across experiments without guesswork.
Select the regular format version to keep Trpv5 interpretation aligned with your workflow goals.
- Targets:
- TRPV5
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the C-terminal region of mouse Trpv5 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9NQA5
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 68.7% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C