Trpv5 Antibody - FFPE Validated
BiCell Scientific
SKU:11035-FFPE-50UL
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About the Target
Build reproducible readouts by using this antibody to assess Trpv5 across matched sample sets. Trpv5 is a trafficking-sensitive transporter that can shift between intracellular pools and the plasma membrane. Use matched handling so differences reflect biology rather than processing.
Tracking Trpv5 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Research Context
Many transport proteins cycle through endosomal pathways, making localization a key readout alongside abundance. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.
Consider these angles when interpreting target-level changes:
- relative abundance across engineered constructs
- stimulus-dependent trafficking and turnover
- patterns consistent with apical or basolateral sorting
- surface versus intracellular pool distribution
Variant Considerations
In sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. This matters because epitope exposure and background can vary with preparation and extraction steps. Standardize key parameters so differences reflect biology rather than handling.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Trpv5 patterns can be compared across experiments without guesswork.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Trpv5 patterns can be compared across experiments without guesswork.
Pair this fixed-section format with stable controls to keep Trpv5 measurements coherent over time.
- Targets:
- TRPV5
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the C-terminal region of mouse Trpv5 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9NQA5
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 68.7% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C