UCB-9260

1 1

Selleck Chemicals

S3231-5MG

€303,00 EUR
€303,00 EUR
Sale Sold out
Taxes included. Shipping calculated at checkout.
Size
View full details

UCB-9260 is an inhibitor of TNF-alpha and NF-kB used in studies of NF-kB Signaling and Immune Signaling and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses in apoptosis, cancer, and immunology models.

By inhibiting TNF-alpha and NF-kB, UCB-9260 can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving TNF-alpha and NF-kB
  • Pathway perturbation studies connected to NF-kB Signaling and Immune Signaling and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Immune-cell activation, cytokine, and mediator assays

Overall, UCB-9260 is appropriate when a defined chemical perturbant is needed to connect TNF-alpha and NF-kB with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
TNF-alpha • NF-kB
Target Class:
Immunomodulator
Pathways:
NF-kB Signaling • Immune Signaling • Apoptosis
Research Area:
Apoptosis • Cancer • Immunology • Inflammation
CAS No.:
1515888-53-5
Molecular Weight:
423.51
Formula:
C₂₆H₂₅N₅O
SMILES:
C[N]1C=C(C=N1)C2=CC3=C(C=C2)N=C(C(O)C4=CC=NC=C4)[N]3CC5=C(C)C=CC(=C5)C
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.