Vadadustat

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Selleck Chemicals

S6490-2MG

€144,00 EUR
€144,00 EUR
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Vadadustat is a modulator of HIF used in studies of pathway modulation. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to pathway-dependent signal amplification or attenuation in angiogenesis, cancer, and cell signaling models.

By modulating HIF, Vadadustat can be used to examine pathway-dependent signal amplification or attenuation. This target class is commonly examined through pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping. In angiogenesis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving HIF
  • Context-dependent response profiling and mechanism comparison
  • Pathway-reporter and mechanistic-phenotyping studies
  • Phenotypic profiling in angiogenesis, cancer, and cell signaling models

Overall, Vadadustat is appropriate when a defined chemical perturbant is needed to connect HIF with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
HIF
Target Class:
Signaling Pathway Modulator
Research Area:
Angiogenesis • Cancer • Cell Signaling
CAS No.:
1000025-07-9
Molecular Weight:
306.70
Formula:
C₁₄H₁₁ClN₂O₄
SMILES:
C1=CC(=CC(=C1)Cl)C2=CC(=C(N=C2)C(=O)NCC(=O)O)O
InChIKey:
JGRXMPYUTJLTKT-UHFFFAOYSA-N
PubChem:
23634441
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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