VANGL2 (LTAP) Antibody
BiCell Scientific
SKU:50632-50UL
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Scientific Overview
Build reproducible readouts by using this antibody to assess VANGL2 (LTAP) across matched sample sets. VANGL2 is a signaling protein that can relay information through phosphorylation and complex assembly. For comparison-heavy studies, consistent sample handling and normalization help reduce run-to-run drift.
In some datasets and protocols, it is referenced by the gene symbol LTAP.
Research Relevance
Perturbations such as inhibitors or ligand stimulation can drive rapid shifts in localization or complex formation. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.
When cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood. Planar polarity studies may connect this target to directional signaling and cytoskeletal alignment.
When building a narrative around the target, it helps to track:
- condition-to-condition comparisons with matched controls
- interaction patterns within multi-protein complexes
- time-resolved changes following stimulation or inhibition
- localization shifts between cytoplasm, membrane, and nucleus
Application-Specific Context
When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. A short pilot series can help set exposure ranges and reduce reruns.
For challenging targets, pairing VANGL2 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
For multi-run studies, the regular format option helps keep VANGL2 (LTAP) trends comparable from experiment to experiment.
- Targets:
- VANGL2
- Research Area:
- Cell Signaling • Developmental Biology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the C-terminal intracellular region of human VANGL2 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9ULK5
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C