Vanzacaftor (VX-121)

1 1

Selleck Chemicals

E1701-1MG

€193,00 EUR
€193,00 EUR
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Vanzacaftor (VX-121) is a research compound associated with CFTR and is relevant to studies of ion-channel pharmacology. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to ion conductance, membrane potential, and electrophysiological responses in cell signaling models.

The current annotation links Vanzacaftor (VX-121) to CFTR, supporting target-focused studies that measure ion conductance, membrane potential, and electrophysiological responses without assigning a more specific primary mechanism than the dataset provides. This target class is commonly examined through electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping. In cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving CFTR
  • Electrophysiology, ion-flux, and membrane-potential studies
  • Phenotypic profiling in cell signaling models
  • Combination studies with orthogonal perturbagens

Overall, Vanzacaftor (VX-121) is appropriate when a defined chemical perturbant is needed to connect CFTR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
CFTR
Target Class:
Ion Channel
Research Area:
Cell Signaling
CAS No.:
2374124-49-7
Molecular Weight:
617.76
Formula:
C₃₂H₃₉N₇O₄S
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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