VCAM1 (CD106) Antibody
BiCell Scientific
SKU:01002-50UL
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Protein Function
Designed to help you characterize VCAM1 (CD106), this antibody supports studies where protein context matters. VCAM1 is a structural regulator of intercellular boundaries and tissue architecture. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol CD106.
Experimental Applications
Researchers often monitor junctional targets when studying epithelial integrity, remodeling, and motility. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Target-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing. Blood-brain barrier models often monitor junction regulation alongside permeability-focused measurements.
Common experimental questions that benefit from target tracking include:
- subcellular redistribution at contact sites versus cytoplasm
- changes in complex assembly with scaffold or adaptor proteins
- comparative profiling across cell states or perturbations
Workflow Perspective
When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so VCAM1 patterns can be compared across experiments without guesswork.
As you refine hypotheses around VCAM1 (CD106), the regular format format helps keep conclusions tied to preparation context.
- Targets:
- VCAM1
- Research Area:
- Cardiovascular • Developmental Biology • Immunology • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (18-aa) derived from the C-terminal intracellular region of human VCAM1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P19320
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C