VER-155008

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Selleck Chemicals

S7751-10MG

€144,00 EUR
€144,00 EUR
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VER-155008 is an inhibitor of HSP90 used in studies of Autophagy. In practice, this places the compound in experiments that measure autophagic flux, lysosomal turnover, and stress adaptation in autophagy, cancer, and protein homeostasis models.

By inhibiting HSP90, VER-155008 can be used to examine autophagic flux, lysosomal turnover, and stress adaptation. This context is compatible with autophagy-flux, lysosome, and cargo-clearance assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In autophagy, cancer, and protein homeostasis models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving HSP90
  • Pathway perturbation studies connected to Autophagy
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in autophagy, cancer, and protein homeostasis models

Overall, VER-155008 is appropriate when a defined chemical perturbant is needed to connect HSP90 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and protein homeostasis models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
HSP90
Target Class:
Other
Pathways:
Autophagy
Research Area:
Autophagy • Cancer • Protein Homeostasis
CAS No.:
1134156-31-2
Molecular Weight:
556.4
Formula:
C₂₅H₂₃Cl₂N₇O₄
SMILES:
C1=CC(=CC=C1COCC2C(C(C(O2)N3C4=NC=NC(=C4N=C3NCC5=CC(=C(C=C5)Cl)Cl)N)O)O)C#N
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.