VLX1570
Selleck Chemicals
SKU:S8288-5MG
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VLX1570 is an inhibitor of DUB used in studies of Protein Degradation / Proteasome. It is especially relevant in cancer and protein homeostasis models, where defined compound exposure can be linked to ubiquitin-dependent turnover, proteostasis, and targeted protein degradation.
By inhibiting DUB, VLX1570 can be used to examine ubiquitin-dependent turnover, proteostasis, and targeted protein degradation. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer and protein homeostasis models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving DUB
- Pathway perturbation studies connected to Protein Degradation / Proteasome
- Concentration-response inhibition and target-dependence studies
- Enzyme-activity assays, substrate-conversion studies, and mechanism profiling
Overall, VLX1570 is appropriate when a defined chemical perturbant is needed to connect DUB with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and protein homeostasis models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- DUB
- Target Class:
- Enzyme
- Pathways:
- Protein Degradation / Proteasome
- Research Area:
- Cancer • Protein Homeostasis
- CAS No.:
- 1431280-51-1
- Molecular Weight:
- 469.39
- Formula:
- C₂₃H₁₇F₂N₃O₆
- SMILES:
- C=CC(=O)N1CCC(=CC2=CC(=C(C=C2)F)[N+](=O)[O-])C(=O)C(=CC3=CC(=C(C=C3)F)[N+](=O)[O-])C1
- InChIKey:
- SCKXBVLYWLLALY-UHFFFAOYSA-N
- PubChem:
- 131954791
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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