Vonoprazan Fumarate (TAK-438)

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Selleck Chemicals

S8016-5MG

€265,00 EUR
€265,00 EUR
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Vonoprazan Fumarate (TAK-438) is an inhibitor of Potassium Channels and ATPases used in studies of ion-channel pharmacology. In practice, this places the compound in experiments that measure ion conductance, membrane potential, and electrophysiological responses in cardiovascular, cell signaling, and neuroscience models.

By inhibiting Potassium Channels and ATPases, Vonoprazan Fumarate (TAK-438) can be used to examine ion conductance, membrane potential, and electrophysiological responses. This target class is commonly examined through electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping. In cardiovascular, cell signaling, and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Potassium Channels and ATPases
  • Concentration-response inhibition and target-dependence studies
  • Electrophysiology, ion-flux, and membrane-potential studies
  • Phenotypic profiling in cardiovascular, cell signaling, and neuroscience models

Overall, Vonoprazan Fumarate (TAK-438) is appropriate when a defined chemical perturbant is needed to connect Potassium Channels and ATPases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular, cell signaling, and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Potassium Channels • ATPases
Target Class:
Ion Channel
Research Area:
Cardiovascular • Cell Signaling • Neuroscience
CAS No.:
1260141-27-2
Molecular Weight:
461.46
SMILES:
CNCC1=CN(C(=C1)C2=CC=CC=C2F)S(=O)(=O)C3=CN=CC=C3.C(=CC(=O)O)C(=O)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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