Voxtalisib (XL765)Analogue

1 1

Selleck Chemicals

S1523-5MG

€206,00 EUR
€206,00 EUR
Sale Sold out
Taxes included. Shipping calculated at checkout.
Size
View full details

Voxtalisib (XL765)Analogue is an inhibitor of PI3K and MTOR and related targets used in studies of PI3K-Akt-mTOR Signaling and DNA Damage Response and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to growth-factor signaling, survival control, and nutrient-sensing outputs and checkpoint activation, DNA repair, and genome-stability control in autophagy, cancer, and cell signaling models.

By inhibiting PI3K and MTOR and related targets, Voxtalisib (XL765)Analogue can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and checkpoint activation, DNA repair, and genome-stability control. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In autophagy, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving PI3K and MTOR and related targets
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and DNA Damage Response and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Voxtalisib (XL765)Analogue is appropriate when a defined chemical perturbant is needed to connect PI3K and MTOR and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
PI3K • MTOR • DNA-PK • PI3K beta
Target Class:
Kinase
Pathways:
PI3K-Akt-mTOR Signaling • DNA Damage Response • Autophagy
Research Area:
Autophagy • Cancer • Cell Signaling • DNA Damage / Repair
CAS No.:
1349796-36-6
Molecular Weight:
599.66
Formula:
C₃₁H₂₉N₅O₆S
SMILES:
CC1=C(C=C(C=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC4=CC=CC=C4N=C3NC5=CC(=CC(=C5)OC)OC)OC
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.