WH-4-023
Selleck Chemicals
SKU:S7565-5MG
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WH-4-023 is an inhibitor of SRC used in studies of MAPK / ERK Signaling. In practice, this places the compound in experiments that measure mitogenic kinase cascades, proliferation control, and differentiation-linked signaling in angiogenesis, cancer, and cell signaling models.
By inhibiting SRC, WH-4-023 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In angiogenesis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving SRC
- Pathway perturbation studies connected to MAPK / ERK Signaling
- Concentration-response inhibition and target-dependence studies
- Biochemical kinase assays, phospho-signaling studies, and selectivity profiling
Overall, WH-4-023 is appropriate when a defined chemical perturbant is needed to connect SRC with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- SRC
- Target Class:
- Kinase
- Pathways:
- MAPK / ERK Signaling
- Research Area:
- Angiogenesis • Cancer • Cell Signaling
- CAS No.:
- 837422-57-8
- Molecular Weight:
- 568.67
- Formula:
- C₃₂H₃₆N₆O₄
- SMILES:
- CC1=C(C(=CC=C1)C)OC(=O)N(C2=C(C=C(C=C2)OC)OC)C3=NC(=NC=C3)NC4=CC=C(C=C4)N5CCN(CC5)C
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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