WIKI4

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Selleck Chemicals

S7490-10MG

€154,00 EUR
€154,00 EUR
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WIKI4 is an inhibitor of PARP and Wnt / beta-catenin used in studies of Wnt Signaling and DNA Damage Response. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to beta-catenin-dependent transcription and developmental signaling and checkpoint activation, DNA repair, and genome-stability control in cancer, cell signaling, and developmental biology models.

By inhibiting PARP and Wnt / beta-catenin, WIKI4 can be used to examine beta-catenin-dependent transcription and developmental signaling and checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and developmental biology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving PARP and Wnt / beta-catenin
  • Pathway perturbation studies connected to Wnt Signaling and DNA Damage Response
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, WIKI4 is appropriate when a defined chemical perturbant is needed to connect PARP and Wnt / beta-catenin with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and developmental biology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
PARP • Wnt / beta-catenin
Target Class:
Enzyme
Pathways:
Wnt Signaling • DNA Damage Response
Research Area:
Cancer • Cell Signaling • Developmental Biology • DNA Damage / Repair
CAS No.:
838818-26-1
Molecular Weight:
521.59
Formula:
C₂₉H₂₃N₅O₃S
SMILES:
COC1=CC=C(C=C1)N2C(=NN=C2SCCCN3C(=O)C4=CC=CC5=C4C(=CC=C5)C3=O)C6=CC=NC=C6
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.