WZ4003
Selleck Chemicals
SKU:S7317-5MG
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WZ4003 is an inhibitor of AMPK used in studies of PI3K-Akt-mTOR Signaling. It is especially relevant in autophagy, cancer, and cell signaling models, where defined compound exposure can be linked to growth-factor signaling, survival control, and nutrient-sensing outputs.
By inhibiting AMPK, WZ4003 can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In autophagy, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving AMPK
- Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling
- Concentration-response inhibition and target-dependence studies
- Biochemical kinase assays, phospho-signaling studies, and selectivity profiling
Overall, WZ4003 is appropriate when a defined chemical perturbant is needed to connect AMPK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- AMPK
- Target Class:
- Kinase
- Pathways:
- PI3K-Akt-mTOR Signaling
- Research Area:
- Autophagy • Cancer • Cell Signaling • Metabolism
- CAS No.:
- 1214265-58-3
- Molecular Weight:
- 496.99
- Formula:
- C₂₅H₂₉ClN₆O₃
- SMILES:
- CCC(=O)NC1=CC(=CC=C1)OC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCN(CC4)C)OC
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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