Y-39983 Dihydrochloride

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Selleck Chemicals

S7935-5MG

€144,00 EUR
€144,00 EUR
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Y-39983 Dihydrochloride is an inhibitor of ROCK used in studies of kinase signaling. In practice, this places the compound in experiments that measure phosphorylation signaling, target engagement, and selectivity relationships in cancer, cardiovascular, and cell cycle models.

By inhibiting ROCK, Y-39983 Dihydrochloride can be used to examine phosphorylation signaling, target engagement, and selectivity relationships. This target class is commonly examined through biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping. In cancer, cardiovascular, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving ROCK
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling
  • Phenotypic profiling in cancer, cardiovascular, and cell cycle models

Overall, Y-39983 Dihydrochloride is appropriate when a defined chemical perturbant is needed to connect ROCK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cardiovascular, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
ROCK
Target Class:
Kinase
Research Area:
Cancer • Cardiovascular • Cell Cycle • Cell Signaling
CAS No.:
173897-44-4
Molecular Weight:
353.25
Formula:
C₁₆H₁₆N₄O·2HCl
SMILES:
CC(C1=CC=C(C=C1)C(=O)NC2=C3C=CNC3=NC=C2)N.Cl.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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