YAP (YAP1) Antibody
BiCell Scientific
SKU:50902-50UL
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Scientific Overview
This antibody supports efforts to assess YAP (YAP1) and interpret it within interaction networks. YAP is a pathway component whose activation state and localization can change after stimulation. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
Monitoring YAP alongside context markers can improve interpretation when phenotypes are subtle.
Research Relevance
When comparing conditions, consistent sample handling and normalization are key for meaningful contrasts. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling.
When building a narrative around the target, it helps to track:
- localization shifts between cytoplasm, membrane, and nucleus
- interaction patterns within multi-protein complexes
- time-resolved changes following stimulation or inhibition
Application-Specific Context
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. If signaling is transient, sampling time can be as important as condition.
When interpreting YAP, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Choose the regular format format to study YAP (YAP1) in a way that stays anchored to pathway logic.
- Targets:
- YAP1
- Research Area:
- Cancer • Cell Cycle • Cell Signaling • Developmental Biology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (19-aa) derived from the C-terminal region of human YAP1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P46937
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C