YC-1 (Lificiguat)

1 1

Selleck Chemicals

S7958-10MG

€144,00 EUR
€144,00 EUR
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YC-1 (Lificiguat) is an inhibitor of HIF used in studies of GPCR Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to receptor-driven second-messenger signaling and desensitization dynamics in cancer and cell signaling models.

By inhibiting HIF, YC-1 (Lificiguat) can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In cancer and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving HIF
  • Pathway perturbation studies connected to GPCR Signaling
  • Concentration-response inhibition and target-dependence studies
  • Pathway-reporter and mechanistic-phenotyping studies

Overall, YC-1 (Lificiguat) is appropriate when a defined chemical perturbant is needed to connect HIF with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
HIF
Target Class:
Signaling Pathway Modulator
Pathways:
GPCR Signaling
Research Area:
Cancer • Cell Signaling
CAS No.:
170632-47-0
Molecular Weight:
304.34
Formula:
C₁₉H₁₆N₂O₂
SMILES:
C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=N2)C4=CC=C(O4)CO
InChIKey:
OQQVFCKUDYMWGV-UHFFFAOYSA-N
PubChem:
5712
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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