YH239-EE

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Selleck Chemicals

S7489-10MG

€144,00 EUR
€144,00 EUR
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YH239-EE is an antagonist of MDM2 and MDMX and related targets used in studies of Apoptosis. It is especially relevant in apoptosis, cancer, and cell cycle models, where defined compound exposure can be linked to caspase-associated cell-death signaling and survival decisions.

By blocking MDM2 and MDMX and related targets, YH239-EE can be used to examine caspase-associated cell-death signaling and survival decisions. This context is compatible with apoptosis, viability, and caspase-readout assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In apoptosis, cancer, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving MDM2 and MDMX and related targets
  • Pathway perturbation studies connected to Apoptosis
  • Receptor-blockade and ligand-competition studies
  • Phenotypic profiling in apoptosis, cancer, and cell cycle models

Overall, YH239-EE is appropriate when a defined chemical perturbant is needed to connect MDM2 and MDMX and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
MDM2 • MDMX • p53
Target Class:
Other
Pathways:
Apoptosis
Research Area:
Apoptosis • Cancer • Cell Cycle
CAS No.:
1364488-67-4
Molecular Weight:
504.41
Formula:
C₂₅H₂₇Cl₂N₃O₄
SMILES:
CCOC(=O)C1=C(C2=C(N1)C=C(C=C2)Cl)C(C(=O)NC(C)(C)C)N(CC3=CC=C(C=C3)Cl)C=O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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