YM201636

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Selleck Chemicals

S1219-5MG

€167,00 EUR
€167,00 EUR
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YM201636 is an inhibitor linked to PI3K-Akt-mTOR Signaling and Autophagy and related pathway-oriented research. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to growth-factor signaling, survival control, and nutrient-sensing outputs and autophagic flux, lysosomal turnover, and stress adaptation in autophagy models.

The pathway annotation connects YM201636 to PI3K-Akt-mTOR Signaling and Autophagy, supporting experiments that monitor growth-factor signaling, survival control, and nutrient-sensing outputs and autophagic flux, lysosomal turnover, and stress adaptation across biochemical, cellular, or phenotypic assay formats. This context is compatible with AKT/mTOR readouts, pathway-response, and viability assays and autophagy-flux, lysosome, and cargo-clearance assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In autophagy models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and Autophagy
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in autophagy models
  • Combination studies with orthogonal perturbagens

Overall, YM201636 is well suited to pathway-oriented studies that need a defined compound input for PI3K-Akt-mTOR Signaling and Autophagy readouts in autophagy models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Pathways:
PI3K-Akt-mTOR Signaling • Autophagy
Research Area:
Autophagy
CAS No.:
371942-69-7
Molecular Weight:
467.48
Formula:
C₂₅H₂₁N₇O₃
SMILES:
C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)NC(=O)C6=CN=C(C=C6)N
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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